A Good Friend Who is specialist in Immunohematology (Blood Bank) from New York Blood Center answered the following Question.
Thanks to Marlene Rodruigez , This explanations are very helful.
(1) Rh- mother has increase titer of anti-D. After delivery, the DAT is strongly (+) but the baby is Rh-
(2)3 units of FFP requested for A – patient
(3)What is the reason for this discrepancy or What would you do to resolve this discrepancy?
(5)You suspect someone might have Jka, K and c antigens on their red cells. You figure out that they don’t have Jka. You also test their serum and see the following:
Answer: D is the correct answer.The fact that the patient hasn’t made anti-K doesn’t tell you if they are positive or negative. They could be negative for K antigen and never make anti-K. The only thing that you know if that their blood is reacting with c antigen and most likely they made anti-c because they are c antigen negative.
(6)What is RHOGAM, when are you going to give it and what will it do to the patient?
(7)In an emergency, what blood type of blood would you give if the red cells are needed or plasma is required and the blood type is unknown?
(8)Would you phenotype a patient who had been transfused within the last 3 months?
Anti-A, anti-B and anti-A,B(10).Mother B Rh(-), Father AB Rh (+). Child 1 A Rh(-) Child 2 B Rh (+). Which is correct
your comment: Based on this information you can’t not rule out the father. Do you know how to do a punnet square? If you do a square, you can see how this the mother can be a BB or BO and the father is a AB can have babies which is A, B, AB and O when the mother is BO but when the mother is BB the babies can only be B or AB.
(11)Anti- F will not react with:
(12)The same antibody was found in 3 different patients. The results of testing are listed below. Which antibody is most likely to be present?
d. Anti- Leb
Answer and comment: You want to chose a antibody that is known to commonly react at all phases and that is common enough where it’s most likely to be found in 3 different patients. The likely answer is anti-M
(13)Which of the following is detected primarily in the antiglobulin phase of the crossmatch:
Anti-M, B, P1- are typically IgM and may agglutinate saline suspended cells at room temperature.
Comment: Anti-Fya contains mainly IgG and these are more likely to react in the antiglobulin phase of testing.
(14) The most common cold agglutinin? Answer: Anti-I should be the correct answer
(15)Multiple antibodies on the panel, what do you do next?
You run a select cell panel to rule in and rule out antibodies
(16)Adminsitration of Rhogam to pregnant mother , how will it affect the child?
It is not known to affect the child
Blood bank Notes from My Own